417 Results (0 seconds)

Status: Open
Published Date: 16/05/2024
Closing Date: 17/06/2024
Value: £2,800,000
National Reference Laboratory for chemical hazards - The FSA and FSS are responsible for Official Feed and Food Controls across the UK. The UK has a legal obligation to appoint NRLs for feed and food. NRLs provide advice and support to food, feed, and food contact materials enforcement laboratories and the FSA and FSS to ensure a harmonised approach to food safety enforcement. NRLs are responsible for setting standards for routine procedures and reliable testing methods in the regulated areas of feed and food. This delivers consumer protection and effective, risk-based, and proportionate regulation and enforcement. The appointed laboratory will carry out the provision of services for the UK National Reference Laboratory (NRL) for Chemical Hazards in feed and food. Chemical hazards in feed and food could include, but are not limited to: -Food Contact Materials (FCM), -Processing contaminants, -Mycotoxins and plant toxins, -Metals and nitrogenous compounds, -Halogenated persistent organic pollutants, -Flavourings. This is a 4 year contract with an optional 2 year extension. The estimated value of the Contract is estimated to be between £0 - £2,800,000 (inc VAT) for the total duration, including the 2 year extension. The FSA is not required to take the extension.

Status: Open
Published Date: 10/05/2024
Closing Date: Unknown
Value: neg.
Antibody Production - The Authority requires the production of batches of purified monoclonal antibody (mAb) derived from hybridoma cell lines. The Authority will supply the contractor with cell lines as Government Furnished Assets (GFA) with the requirement that they are cultured and monoclonal antibodies purified from growth media. Requests will be for approximately 20 batches per year of 20 mg and approximately 10 batches of 100 mg of purified IgG over a 6 year period.

Status: Awarded
Published Date: 30/04/2024
Closing Date: 07/03/2024
Value: £105,680
Supply of Oligonucleotides - Awarded contract, published for transparency

Status: Closed
Published Date: 24/04/2024
Closing Date: Unknown
Value: neg.
Effects of Chemical Exposure on Whole Genome - This is an outcome-based specification, where project deliverables are critical. These may not be achievable in full due to the novel approach we intend to take, but we expect creativity and innovation in the approach to delivering the objectives with us.

Status: Open
Published Date: 09/04/2024
Closing Date: 10/05/2024
Value: £140,000
CEFAS24-39 ITT for services for holistic approaches to investigating disease in aquatic animal systems in India, under the Ocean Country Partnership Programme (OCPP) - The Ocean Country Partnership Programme (OCPP) is funded through official development assistance (ODA) as part of the UK's £500 million Blue Planet Fund. Through the OCPP, the UK government partners with ODA-eligible countries to deliver tangible and positive impacts on the livelihoods of coastal communities that depend on healthy marine ecosystems. The programme supports countries to strengthen marine science expertise, develop science-based policy and management tools, and create educational resources for coastal communities. Under the sustainable seafood objective, the programme supports the development of the skills and expertise needed to adopt sustainable seafood practices. This will reduce risks such as the spread of zoonotic diseases from unsustainable or unsafe activities, and will support trade in safe seafood. The programme will also help crack down on illegal, unreported and unregulated fishing by supporting the development of better management, monitoring and enforcement capabilities. Following a One Health Aquaculture workshop, held in Kerala, India in February 2023, key priorities were identified for India that support the overall aim of the Sustainable Seafood project. These priorities are: • Aquatic disease • Water quality • Climate change • AMR In this project we aim to combine the four key priorities in one project focusing on investigating emerging and/or cryptic aquatic animal disease. Given the scope of this funding, only disease in marine or brackishwater aquatic animal culture can be investigated. This project aims to investigate an aquatic animal culture system in India that is experiencing clinical signs of disease and/or mortalities using a holistic approach (sampling both the affected species and the environment that it is cultured in). Traditional methods to investigate disease, such as histopathology and basic water quality measurements, will be combined with metatranscriptomics, and microbial/algal community analysis (including 16S bacterial and 18S eukaryote metagenomics) and chemical analysis to provide information on the parameters involved in disease and health states of the aquatic animal of interest. To view this opportunity please go to https://defra-family.force.com/s/Welcome You will need to log in or create a new supplier account. The opportunity can then be found searching 'CEFAS24-39 ITT for services for holistic approaches to investigating disease in aquatic animal systems in India, under the Ocean Country Partnership Programme (OCPP)'.

Status: Open
Published Date: 03/04/2024
Closing Date: 29/04/2024
Value: £75,000
CEFAS24-29 Contract for whole genome sequencing of Streptococcus agalactiae serotypes in Indian aquatic systems, under the Ocean Country Partnership Programme (OCPP) - The Ocean Country Partnership Programme (OCPP) is funded through official development assistance (ODA) as part of the UK's £500 million Blue Planet Fund. Through the OCPP, the UK government partners with ODA-eligible countries to deliver tangible and positive impacts on the livelihoods of coastal communities that depend on healthy marine ecosystems. The programme supports countries to strengthen marine science expertise, develop science-based policy and management tools, and create educational resources for coastal communities. Under the sustainable seafood objective, the programme supports the development of the skills and expertise needed to adopt sustainable seafood practices. This will reduce risks such as the spread of zoonotic diseases from unsustainable or unsafe activities and will support trade in safe seafood. The programme will also help crack down on illegal, unreported and unregulated fishing by supporting the development of better management, monitoring and enforcement capabilities. Following a One Health Aquaculture workshop, held in Kerala, India in February 2023, key priorities were identified for India that support the overall aim of the Sustainable Seafood project. These priorities are: • Antimicrobial resistance (AMR) • Aquatic disease • Water quality • Climate change In this project we aim to combine the AMR, aquatic disease and water quality priorities in one project focusing on characterising serotypes of Streptococcus agalactiae bacteria present in culture settings in Asia. This project aims to characterise Streptococcus agalactiae serotypes from a range of regions and culture systems in India, as well as other countries in South-East Asia using high-throughput whole genome sequencing. The genomic data will be used to determine the AMR and toxin genes present in the serotypes, and compare them to existing data from humans, terrestrial-farmed animals, and aquatic animals to determine the risk of zoonosis from antimicrobial resistant S. agalactiae. This Contract will be a collaboration between the Supplier and Cefas, with Cefas able to provide training and support in preparation of samples for whole genome (in the form of SOPs), and bioinformatic analysis of sequence data generated within this project. Training may be online or in-person and will be confirmed with Cefas with the Supplier upon Contract commencement. To view this opportunity please go to https://defra-family.force.com/s/Welcome You will need to log in or create a new supplier account. The opportunity can then be found searching 'CEFAS24-29 ITT for whole genome sequencing in Indian aquatic systems under OCPP'.

Status: Open
Published Date: 22/03/2024
Closing Date: Unknown
Value: neg.
Bacteriophage Advisory & Specialist Testing Services - Bacteriophage Contamination advisory and Specialist Testing Services

Status: Awarded
Published Date: 22/03/2024
Closing Date: 16/02/2024
Value: £17,920
GB-London: RBGKEW1276 - Whole Genome Sequencing for cacao DNA from herbarium specimens - The Royal Botanic Gardens, Kew (RBG Kew) intends to appoint a supplier for a high-throughput sequencing service from ancient-DNA extractions sourced from historical herbarium collections of cacao specimens (Theobroma cacao, Malvaceae) and wild relative species (Theobroma/Herrania spp.). Utilizing a CTAB-extraction method, the extracted samples will be sent in batches. The supplier must conduct pre-quality control (QC) tests (including RNase treatment and DNA purification, if necessary) on these total-genome DNA extractions, ensuring acceptable yields and concentrations. Tasks also include library preparation using the Nextera XT Library Kit and performing paired-end whole genomic sequencing (WGS) using the Illumina NovaSeq 6000 (or an equally powerful sequencing platform) to seek obtaining ideally ~12 Gb per sample, depending on the conditions of the sample. This process aims to cover 120-140 samples, targeting a coverage of 15-30x each, given the known genome size of Theobroma species at ~450-490 Mbp. The supplier should be acquainted with high-throughput sequencing from aged herbarium samples, due to the historical nature of these collections (preserved over 50-100 years ago). They are expected to have previous experience in the production of satisfactory data under these conditions and will need to state this in the application. Each sample sent will contain 25-50 uL of DNA, predominantly at concentrations of 10 ng/uL (some with less, but never less than 0.5 ng/uL of total DNA). It is expected that many samples will have heavily fragmented DNA, and the supplier should be able to present alternatives to deal with these. Following sequencing, the supplier should conduct post-QC to verify data quality before delivery. Data transfer methods such as USB, HDD, or preferably Cloud transfer are viable options. The genomic data obtained will support an ongoing project at RBG Kew. This project aims to comprehensively study the geographical history, and other population genomic studies of Theobroma cacao at a global scale, utilising molecular data obtained from historical herbarium collections combined with data obtained from other sources.

Status: Awarded
Published Date: 22/03/2024
Closing Date: 28/02/2024
Value: £12,447
GSS24141- PCR-Free Human WGS - ***Please note this is an award notice, not a call for competition*** UK Research and Innovation (UKRI) had a requirement for PCR-Free Human WGS. This procurement has been concluded as a competitive quotation (below threshold)

Status: Closed
Published Date: 21/03/2024
Closing Date: 22/03/2024
Value: neg.
Bacterial Contamination of Bivalve Molluscs FS616026 NRL - The National Reference Laboratories (NRLs) designated by the FSA and FSS in accordance with Assimilated Law 2017/625 are a critical part of our national infrastructure for delivering a safe and authentic food system. The NRLs play a pivotal role in food safety enforcement by providing support and impartial expert advice to Official Laboratories (OLs) and for the FSA and FSS on testing of food and feed, identifying new areas of research interest and emerging threats, developing novel analytical methods and providing advice and testing capability during an emergency incident. The appointed laboratory will carry out the provision of services for the UK National Reference Laboratory (NRL) for bacteriological contamination of live bivalve molluscs.